Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995439 | 0.87 | KDM4E (0.49) | MEN1KMT2APKMALDH1A1KDM4E | |
| SCHEMBL7995494 | 0.84 | SCN9A (0.48) | MEN1KMT2APKM | |
| SCHEMBL7996100 | 0.78 | HTR1B (0.42) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL7983560 | 0.77 | NPSR1 (0.63) | MEN1KMT2AALDH1A1HPGDNPC1 | |
| SCHEMBL7963964 | 0.77 | LMNA (0.46) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL7984304 | 0.77 | STING1 (0.49) | ALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL8001602 | 0.75 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL7024493 | 0.75 | MEN1 (0.49) | MEN1KMT2APKMALDH1A1KDM4E | |
| SCHEMBL31361958 | 0.74 | SMN1; SMN2 (0.42) | MEN1KMT2AKDM4EHPGDHTR1B | |
| SCHEMBL7072684 | 0.74 | MTNR1A (0.77) | KMT2AHPGDMTNR1AMTNR1BNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |