Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964039 | 0.90 | RAB9A (0.54) | RAB9ASMN1; SMN2NPC1GRIN2AGRIN2B | |
| SCHEMBL8915606 | 0.86 | RAB9A (0.69) | RAB9ASMN1; SMN2NPC1GRIN2AGRIN2B | |
| SCHEMBL7974455 | 0.84 | TSHR (0.61) | RAB9ANPC1ALDH1A1MAPTALOX15 | |
| SCHEMBL9514685 | 0.83 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1GRIN2AGRIN2B | |
| SCHEMBL7977639 | 0.83 | RAB9A (0.59) | RAB9ASMN1; SMN2NPC1HPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL699487 | 0.82 | RAB9A (0.97) | RAB9ASMN1; SMN2NPC1GRIN2AGRIN2B | |
| SCHEMBL7964032 | 0.81 | NPC1 (0.60) | RAB9ASMN1; SMN2NPC1HPGDALDH1A1 | |
| SCHEMBL8916879 | 0.80 | RAB9A (0.60) | RAB9ASMN1; SMN2NPC1GRIN2AGRIN2B | |
| SCHEMBL7964004 | 0.80 | NPC1 (0.55) | RAB9ASMN1; SMN2NPC1HPGDALDH1A1 | |
| SCHEMBL7964015 | 0.80 | EPHX2 (0.64) | RAB9ASMN1; SMN2NPC1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |