Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 5/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964029 | 0.90 | RAB9A (0.70) | RAB9AGRIN2AGRIN2BSMN1; SMN2NPC1 | |
| SCHEMBL9514091 | 0.84 | RAB9A (0.74) | RAB9AGRIN2AGRIN2BSMN1; SMN2NPC1 | |
| SCHEMBL7964032 | 0.83 | NPC1 (0.60) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL7977556 | 0.83 | SMN1; SMN2 (0.58) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL7964004 | 0.82 | NPC1 (0.55) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL7964015 | 0.82 | EPHX2 (0.64) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL7974419 | 0.81 | SMN1; SMN2 (0.47) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL7964033 | 0.80 | EGLN3 (0.47) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL7980296 | 0.80 | SMN1; SMN2 (0.57) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL7977579 | 0.78 | RAB9A (0.66) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |