Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD5 | P21918 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8980143 | 0.86 | CYP2C9 (0.62) | RAB9ASMN1; SMN2LTA4HARMAPT | |
| SCHEMBL7964029 | 0.83 | RAB9A (0.70) | RAB9ASMN1; SMN2MAPTALDH1A1HPGD | |
| SCHEMBL7963990 | 0.83 | SMN1; SMN2 (0.50) | RAB9ASMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL8980078 | 0.82 | RAB9A (0.61) | RAB9ASMN1; SMN2LTA4HARMAPT | |
| SCHEMBL7964010 | 0.79 | SMN1; SMN2 (0.61) | RAB9ASMN1; SMN2ARMAPTLMNA | |
| SCHEMBL7964121 | 0.79 | SMN1; SMN2 (0.61) | RAB9ASMN1; SMN2ARMAPTLMNA | |
| SCHEMBL7964060 | 0.77 | SMN1; SMN2 (0.62) | RAB9ASMN1; SMN2ARMAPTLMNA | |
| SCHEMBL8980079 | 0.77 | CYP2C9 (0.64) | RAB9ASMN1; SMN2LTA4HARMAPT | |
| SCHEMBL7974455 | 0.76 | TSHR (0.61) | RAB9AMAPTHTTALDH1A1NPC1 | |
| SCHEMBL12195145 | 0.76 | RAB9A (0.78) | RAB9ASMN1; SMN2LTA4HARMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |