Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30571306 | 0.76 | TRPV4 (0.46) | SLC6A4LMNASMN1; SMN2ALDH1A1KCNH2 | |
| SCHEMBL7766240 | 0.76 | S1PR4 (0.37) | S1PR4SLC6A4TDP1LMNASMN1; SMN2 | |
| SCHEMBL15140350 | 0.76 | TRPV4 (0.46) | SLC6A4LMNASMN1; SMN2ALDH1A1KCNH2 | |
| SCHEMBL8232189 | 0.72 | ALDH1A1 (0.46) | S1PR4TSHRTDP1HTR2CHTR2B | |
| SCHEMBL12360711 | 0.71 | TDP1 (0.56) | S1PR4TSHRTDP1LMNA | |
| SCHEMBL2252284 | 0.69 | MRGPRX4 (0.48) | S1PR4SLC6A4TDP1KCNH2 | |
| SCHEMBL17150071 | 0.69 | SLC6A4 (0.43) | S1PR4SLC6A4HTR2AKCNH2 | |
| SCHEMBL15594072 | 0.68 | SCN4A (0.51) | TSHRHTR2CHTR2BLMNACYP1A2 | |
| SCHEMBL3029303 | 0.68 | TSHR (0.48) | TSHRTDP1LMNACYP1A2CYP2C9 | |
| SCHEMBL20521955 | 0.67 | TSHR (0.65) | TSHRTDP1SMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6169184-B1 | REACTING SUBSTITUTED PYRIDINE WITH SPECIFIED ARYL COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 2001-01-02 | — | — | US | disclosed |