Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 18/20 | 0.72 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.60 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | NQO2 | P16083 | 2/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3949444 | 0.89 | MTNR1A (0.71) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL7100652 | 0.84 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL8064758 | 0.83 | MTNR1A (0.63) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL7021092 | 0.81 | HTR1A (0.64) | MTNR1AMTNR1BHTR2BNQO2TRPV1 | |
| SCHEMBL7098615 | 0.78 | MTNR1A (0.76) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL6075471 | 0.77 | MTNR1A (0.77) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL24150467 | 0.75 | HSD11B1 (0.41) | MTNR1AMTNR1BHTR2CTRPV1 | |
| Agomelatine SCHEMBL15822116 | 0.75 | MTNR1A (0.84) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL6076230 | 0.75 | MTNR1A (0.77) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL8054353 | 0.74 | MTNR1A (0.75) | MTNR1AMTNR1BHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310074-B1 | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-10-30 | — | — | US | disclosed |
| CN-1277962-A | Novel substituted dipolymer compounds, prepn. method therefor, pharmaceutical compositions contg. same | ADIR (FR) | 2000-12-27 | — | — | CN | disclosed |
| EP-1057826-A1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-12-06 | — | — | EP | disclosed |