Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.62 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 2/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 2/20 | 0.43 |
| ▸ | SKP1 | P63208 | 2/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | DTYMK | P23919 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24838586 | 0.79 | CYP11B2 (0.53) | CYP11B2CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7964475 | 0.78 | CYP11B2 (0.41) | CYP11B2CYP11B1 | |
| SCHEMBL21064298 | 0.77 | OPRD1 (0.47) | CYP11B2GBA1CHRM2CHRM4CHRM1 | |
| SCHEMBL3249913 | 0.77 | OPRD1 (0.49) | CYP11B2CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7965544 | 0.76 | CYP11B2 (0.55) | CYP11B2PIK3CDNAMPTGPR119 | |
| SCHEMBL2080003 | 0.76 | PDK2 (0.47) | CYP11B2CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL653342 | 0.76 | STS (0.47) | GPR119TSHRALOX15ATMOPRD1 | |
| SCHEMBL3249164 | 0.76 | GPR119 (0.47) | CYP11B2CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL3540066 | 0.76 | TSHR (0.47) | CYP11B2CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL1513306 | 0.76 | PDK2 (0.49) | GPR119TSHRALOX15ATMOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1315830-A | Method for treating anxiety disorders | LILLY CO ELI (US) | 2001-10-03 | — | — | CN | disclosed |
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| WO-2000006082-A2 | TREATMENT OF ANXIETY DISORDERS | ELI LILLY AND COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
| WO-2000006166-A1 | 5-HT1F ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0976747-A2 | Use of 5HT-1F receptor antagonists for treating anxiety disorders | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |