Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 3/20 | 0.42 |
| ▸ | NOS1 | P29475 | 3/20 | 0.42 |
| ▸ | NOS2 | P35228 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6996770 | 1.00 | ALDH1A1 (0.56) | ALDH1A1HTTTAS1R3TAS1R1MEN1 | |
| SCHEMBL6996018 | 0.90 | KMT2A (0.47) | ALDH1A1MEN1KMT2A | |
| SCHEMBL6996015 | 0.90 | KMT2A (0.47) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7958352 | 0.89 | ALDH1A1 (0.53) | ALDH1A1TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL6988661 | 0.89 | ALDH1A1 (0.53) | ALDH1A1TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL6475056 | 0.87 | ALDH1A1 (0.55) | ALDH1A1HTTTAS1R3TAS1R1MEN1 | |
| SCHEMBL8558206 | 0.87 | NOS3 (0.52) | ALDH1A1HTTTAS1R3TAS1R1MEN1 | |
| SCHEMBL4421836 | 0.87 | ALDH1A1 (0.55) | ALDH1A1HTTTAS1R3TAS1R1MEN1 | |
| SCHEMBL8652110 | 0.87 | NOS3 (0.52) | ALDH1A1HTTTAS1R3TAS1R1MEN1 | |
| SCHEMBL7964632 | 0.84 | ALDH1A1 (0.50) | ALDH1A1HTTTAS1R3TAS1R1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172255-B1 | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-5830826-A | Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |