Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 4/20 | 0.52 |
| ▸ | NOS1 | P29475 | 4/20 | 0.52 |
| ▸ | NOS2 | P35228 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8652110 | 1.00 | NOS3 (0.52) | NOS3NOS1NOS2ALDH1A1HTT | |
| SCHEMBL8557162 | 0.89 | ALDH1A1 (0.57) | ALDH1A1HTTNPSR1TAS1R3TAS1R1 | |
| SCHEMBL8657482 | 0.89 | ALDH1A1 (0.57) | ALDH1A1HTTNPSR1TAS1R3TAS1R1 | |
| SCHEMBL8558470 | 0.88 | FPR2 (0.44) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8558467 | 0.88 | FPR2 (0.44) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL6475338 | 0.87 | NOS3 (0.51) | NOS3NOS1NOS2ALDH1A1HTT | |
| SCHEMBL4425149 | 0.87 | NOS3 (0.51) | NOS3NOS1NOS2ALDH1A1HTT | |
| SCHEMBL7964516 | 0.87 | ALDH1A1 (0.56) | NOS3NOS1NOS2ALDH1A1HTT | |
| SCHEMBL6996770 | 0.87 | ALDH1A1 (0.56) | NOS3NOS1NOS2ALDH1A1HTT | |
| SCHEMBL8553227 | 0.84 | ALDH1A1 (0.55) | NOS3NOS1NOS2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1080719-C | Substituted 1H-3-aryl-pyrrolidine-2,4-diones derivative | BAYER GMBH (DE) | 2002-03-13 | — | — | CN | disclosed |
| US-5847211-A | Substituted 1H-3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| EP-0668267-B1 | Substituted 1H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1998-04-08 | — | — | EP | disclosed |
| US-5622917-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |
| CN-1110680-A | Substituted 1H-3-aryl-pyrrolidine-2,4-diones derivative | BYLL GMBH (DE) | 1995-10-25 | — | — | CN | disclosed |
| EP-0668267-A1 | Substituted 1H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1995-08-23 | — | — | EP | disclosed |