Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 1/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7418952 | 0.92 | RAB9A (0.44) | LMNAGLARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7959855 | 0.90 | LMNA (0.44) | LMNAGLARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7949796 | 0.88 | RAB9A (0.44) | LMNARAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL7416321 | 0.88 | MAPT (0.47) | LMNAGLARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7411535 | 0.88 | SMN1; SMN2 (0.55) | LMNAGLARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7961855 | 0.88 | SMN1; SMN2 (0.55) | LMNAGLARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8873046 | 0.86 | CHRNB2 (0.41) | RAB9ANPC1NTRK1MAPTKDM4E | |
| SCHEMBL7412773 | 0.86 | LMNA (0.41) | LMNAGLARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7950029 | 0.86 | RAB9A (0.44) | LMNAGLARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7964322 | 0.85 | NTRK1 (0.43) | RAB9ANPC1KMT2AGAANTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639760-A | USEFUL AS MUSCLE RELAXANTS, SEDATIVES, ANXIOLYTICS, ANTICONVULSANTS, AND ANTIDOTES FOR DRUG OVERDOSE | MARYANOFF BRUCE E (US) | 1997-06-17 | — | — | US | claimed |
| US-6218384-B1 | FOR THERAPY OF ANXIETY, MUSCLE SPASMS, SLEEPLESSNESS, CONVULSIONS AND BENZODIAZEPINE OVERDOSES | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2001-04-17 | — | — | US | disclosed |
| US-5639760-A | USEFUL AS MUSCLE RELAXANTS, SEDATIVES, ANXIOLYTICS, ANTICONVULSANTS, AND ANTIDOTES FOR DRUG OVERDOSE | MARYANOFF BRUCE E (US) | 1997-06-17 | — | — | US | disclosed |