Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13134572 | 0.85 | DRD2 (0.54) | MAPK1P2RX7MAPTDRD4DRD2 | |
| SCHEMBL15315675 | 0.83 | SIGMAR1 (0.52) | DRD4DRD2CYP2D6CHRM2CHRM3 | |
| SCHEMBL13699526 | 0.83 | SIGMAR1 (0.52) | DRD4DRD2CYP2D6CHRM2CHRM3 | |
| SCHEMBL9307239 | 0.81 | MAPK1 (0.43) | MAPK1P2RX7MAPTHTTHDAC1 | |
| SCHEMBL22055123 | 0.76 | HDAC1 (0.55) | MAPK1MAPTHTTHDAC1HDAC8 | |
| SCHEMBL11958053 | 0.72 | DRD4 (0.56) | DRD4CYP2D6 | |
| Hydrochloric Acid SCHEMBL11708182 | 0.72 | SIGMAR1 (0.48) | P2RX7DRD4DRD2 | |
| SCHEMBL13699639 | 0.72 | MAPT (0.42) | MAPK1MAPTHTTHDAC1HDAC8 | |
| SCHEMBL3231048 | 0.72 | L3MBTL1 (0.46) | MAPK1MAPTHTTNPSR1CHRM2 | |
| SCHEMBL11779683 | 0.72 | CHRM2 (0.46) | DRD4CYP2D6CHRM2CHRM3OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310067-B1 | 1-(DIPHENYLMETHYL-PIPERAZINYLETHYL)UROCANIC ACID METHYL ESTER FOR EXAMPLE; GOOD SOLUBILITY; TREATING ALLERGIC DISEASES | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-1054003-A1 | UROCANIC ACID DERIVATIVES | Senju Pharmaceutical Co., Ltd. (JP) | 2000-11-22 | — | — | EP | disclosed |