Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27610240 | 0.84 | CHRNA7 (0.50) | MAPK1MAPTHTTNPSR1DRD4 | |
| SCHEMBL15315675 | 0.83 | SIGMAR1 (0.52) | DRD4DRD2SMN1; SMN2CYP2D6CHRM2 | |
| SCHEMBL13699526 | 0.83 | SIGMAR1 (0.52) | DRD4DRD2SMN1; SMN2CYP2D6CHRM2 | |
| SCHEMBL7964674 | 0.81 | MAPK1 (0.48) | MAPK1MAPTHTTNPSR1DRD4 | |
| SCHEMBL13134572 | 0.81 | DRD2 (0.54) | MAPK1MAPTDRD4DRD2P2RX7 | |
| SCHEMBL13699639 | 0.75 | MAPT (0.42) | MAPK1MAPTHTTNPSR1HDAC1 | |
| SCHEMBL22055123 | 0.75 | HDAC1 (0.55) | MAPK1MAPTHTTNPSR1DRD4 | |
| SCHEMBL3231048 | 0.74 | L3MBTL1 (0.46) | MAPK1MAPTHTTNPSR1CHRNA7 | |
| SCHEMBL11784182 | 0.72 | CHRNA7 (0.43) | MAPK1DRD4DRD2CHRNA7P2RX7 | |
| SCHEMBL11958053 | 0.72 | DRD4 (0.56) | DRD4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342929-A | Direct glycosylation leads to the desired glycosides in high yield and relatively short reaction times using metal complex salts; large amounts of the alpha- or beta-form are often obtained | CIBA-GEIGY CORPORATION (US) | 1994-08-30 | — | — | US | disclosed |