Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.64 |
| ▸ | TYMS | P04818 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.40 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678291 | 0.83 | TYMS (0.55) | GRM4TYMSALDH1A1LPAR3LPAR2 | |
| SCHEMBL379787 | 0.82 | GRM4 (0.44) | GRM4TYMSLMNA | |
| SCHEMBL25670650 | 0.82 | GABBR2 (0.46) | GRM4TYMSLMNABLM | |
| SCHEMBL9713364 | 0.81 | TYMS (0.52) | GRM4TYMSALDH1A1LPAR3LPAR2 | |
| SCHEMBL11412472 | 0.79 | LPAR3 (0.56) | GRM4TYMSALDH1A1LPAR3LPAR2 | |
| SCHEMBL11422894 | 0.79 | LPAR3 (0.56) | GRM4TYMSALDH1A1LPAR3LPAR2 | |
| SCHEMBL5063485 | 0.78 | GRM4 (1.00) | GRM4TYMSALDH1A1LPAR3LPAR2 | |
| SCHEMBL6823813 | 0.78 | GRM4 (0.46) | GRM4ALDH1A1LMNA | |
| SCHEMBL16168097 | 0.78 | GRM4 (0.58) | GRM4TYMSALDH1A1LPAR3LPAR2 | |
| SCHEMBL17452114 | 0.78 | GRM4 (0.58) | GRM4TYMSALDH1A1LPAR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11807641-B2 | MASP-2 inhibitors and methods of use | OMEROS CORPORATION (US) | 2023-11-07 | — | — | US | disclosed |
| US-11661418-B2 | MASP-2 inhibitors and methods of use | OMEROS CORPORATION (US) | 2023-05-30 | — | — | US | disclosed |
| US-20170327448-A1 | METHODS FOR PRODUCING FUELS, GASOLINE ADDITIVES, AND LUBRICANTS USING AMINE CATALYSTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-11-16 | — | — | US | disclosed |
| WO-2017067631-A1 | BLUE OPTOELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2017-04-27 | — | — | WO | disclosed |
| US-20160243047-A1 | SURFACE FUNCTIONALIZED, HOST-GUEST POLYMER NANO-ASSEMBLIES AND METHODS THEREOF | UNIV MASSACHUSETTS (US) | 2016-08-25 | — | — | US | disclosed |
| US-8395041-B2 | Photoelectric conversion element and solor cell | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2013-03-12 | — | — | US | disclosed |
| US-20100288360-A1 | PHOTOELECTRIC CONVERSION ELEMENT AND SOLOR CELL | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2010-11-18 | — | — | US | disclosed |
| US-6204222-B1 | SUITABLE AS HERBICIDES AND FOR DESICCATION/DEFOLIATION OF PLANTS | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-20 | — | — | US | disclosed |
| US-6040274-A | 2-Aroylcyclohexanediones, their preparation and their use as herbicides or plant growth-regulating agents | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-21 | — | — | US | disclosed |
| EP-0783487-B1 | 2-AROYLCYCLOHEXANDIONES, PROCESS FOR PREPARING THE SAME AND THEIR USE AS HERBICIDES OR PLANT GROWTH REGULATORS | BASF AG (DE) | 2000-02-09 | — | — | EP | disclosed |
| US-5559218-A | AGRICULTURAL USE | BASF AKTIENGESELLSCHAFT (DE) | 1996-09-24 | — | — | US | disclosed |
| US-5523462-A | HERBICIDES; PLANT GROWTH REGULATORS | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-04 | — | — | US | disclosed |
| US-5514642-A | HERBICIDES FOR PLANT GROWTH REGULATORS | BASF AKTIENGESELLSCHAFT (DE) | 1996-05-07 | — | — | US | disclosed |
| WO-1996010561-A1 | 2-AROYLCYCLOHEXANDIONES, PROCESS FOR PREPARING THE SAME AND THEIR USE AS HERBICIDES OR PLANT GROWTH REGULATORS | BASF AKTIENGESELLSCHAFT (DE) | 1996-04-11 | — | — | WO | disclosed |
| EP-0609259-B1 | CYCLOHEXENONE DERIVATES USED AS HERBICIDES | BASF AG (DE) | 1995-11-22 | — | — | EP | disclosed |
| EP-0666254-A1 | 2-Aroylcydohexanediones, process for their preparation and their use as herbicide or as plant growth regulating agent | BASF AKTIENGESELLSCHAFT (DE) | 1995-08-09 | — | — | EP | disclosed |
| EP-0637298-A1 | SUBSTITUTED CYCLOHEXENE-1,2-BICARBOXYLIC ACID DERIVATIVES AND RAW MATERIALS FOR PRODUCING THEM | BASF Aktiengesellschaft (DE) | 1995-02-08 | — | — | EP | disclosed |
| WO-1994004489-A1 | CYCLOHEXENONOXIME ETHERS, THEIR PREPARATION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1994-03-03 | — | — | WO | disclosed |
| WO-1993022280-A1 | SUBSTITUTED CYCLOHEXENE-1,2-BICARBOXYLIC ACID DERIVATIVES AND RAW MATERIALS FOR PRODUCING THEM | BASF AKTIENGESELLSCHAFT (DE) | 1993-11-11 | — | — | WO | disclosed |
| WO-1993008153-A1 | CYCLOHEXENONE DERIVATES USED AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1993-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11807641-B2 | MASP-2 inhibitors and methods of use | MASP2, METAP2, SPINT2 | GRM4 3822/4885TYMS 4143/4885ALDH1A1 4709/4885 |
| US-20160243047-A1 | SURFACE FUNCTIONALIZED, HOST-GUEST POLYMER NANO-ASSEMBLIES AND METHODS THEREOF | MSN, CD44, EPHA2 | GRM4 1018/4885TYMS 930/4885ALDH1A1 1697/4885 |
| US-20170327448-A1 | METHODS FOR PRODUCING FUELS, GASOLINE ADDITIVES, AND LUBRICANTS USING AMINE CATALYSTS | GK, MSMO1, DGKG | GRM4 611/4885TYMS 1980/4885ALDH1A1 860/4885 |
| US-11661418-B2 | MASP-2 inhibitors and methods of use | MASP2, METAP2, SPINT2 | GRM4 3822/4885TYMS 4143/4885ALDH1A1 4709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.