Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976878 | 0.76 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL7965208 | 0.75 | MEN1 (0.41) | ALDH1A1MEN1KMT2AMAPTHTR2A | |
| SCHEMBL7965214 | 0.66 | KDM4E (0.49) | SMN1; SMN2CYP1A2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL11313947 | 0.66 | SLC6A2 (0.41) | SMN1; SMN2CYP1A2CYP2C9CYP2C19SLC6A2 | |
| SCHEMBL9172078 | 0.64 | ALDH1A1 (0.42) | SMN1; SMN2CYP1A2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL701484 | 0.63 | MEN1 (0.38) | ALDH1A1MAPK1TDP1MEN1KMT2A | |
| SCHEMBL6938300 | 0.63 | MEN1 (0.38) | CYP1A2CYP2C19NPSR1SLC6A2SLC6A4 | |
| SCHEMBL702297 | 0.63 | MAPT (0.36) | SMN1; SMN2CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL10362291 | 0.63 | TP53 (0.43) | NPSR1ALDH1A1MAPK1TSHRMEN1 | |
| SCHEMBL9651481 | 0.62 | ALDH1A1 (0.42) | ALDH1A1TDP1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001060781-A2 | DIPHENYL COMPOUNDS, FORMULATIONS AND USES THEREOF | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2001-08-23 | — | — | WO | claimed |