Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733830 | 0.98 | ALDH1A1 (0.71) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL11134565 | 0.96 | ALDH1A1 (0.74) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL9505752 | 0.88 | ALDH1A1 (0.63) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| Bromide SCHEMBL8664123 | 0.85 | MEN1 (0.94) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL9241499 | 0.85 | MEN1 (0.60) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| Bromide SCHEMBL29278162 | 0.83 | LMNA (0.68) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| Bromide SCHEMBL28605769 | 0.83 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| Bromide SCHEMBL11681833 | 0.83 | KMT2A (0.56) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL11134568 | 0.82 | ALDH1A1 (0.79) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| Bromide SCHEMBL2831425 | 0.80 | ACHE (0.68) | ALDH1A1SMN1; SMN2LMNABCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117402141-A | Fluorescent probe and preparation method and application thereof | 上海工程技术大学 | 2024-01-16 | — | — | CN | disclosed |
| CN-109423291-B | Etching solution for selectively removing silicon-germanium alloy from silicon-germanium/silicon stack in the manufacture of semiconductor devices | 弗萨姆材料美国有限责任公司 | 2022-09-30 | — | — | CN | disclosed |
| WO-2001060781-A2 | DIPHENYL COMPOUNDS, FORMULATIONS AND USES THEREOF | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2001-08-23 | — | — | WO | disclosed |