SCHEMBL8733830

SCHEMBL8733830

O=[N+]([O-])c1ccc(C[n+]2ccccc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.71
MEN1 O00255 3/20 0.71
KMT2A Q03164 3/20 0.71
MAPT P10636 2/20 0.71
KDM4E B2RXH2 2/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
LMNA P02545 3/20 0.65
L3MBTL1 Q9Y468 1/20 0.65
POLB P06746 1/20 0.53
APOBEC3A P31941 1/20 0.53
APOBEC3G Q9HC16 1/20 0.53
HSP90AA1 P07900 1/20 0.51
LOXL2 Q9Y4K0 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C19 P33261 1/20 0.50
RCE1 Q9Y256 1/20 0.49
PTPRF P10586 1/20 0.49
PTPN2 P17706 1/20 0.49
PTPN1 P18031 1/20 0.49
PTPN11 Q06124 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL7965212 0.98 MEN1 (0.69) ALDH1A1MEN1KMT2AMAPTKDM4E
Hydrochloric Acid SCHEMBL11134565 0.98 ALDH1A1 (0.74) ALDH1A1MEN1KMT2AMAPTKDM4E
SCHEMBL9505752 0.89 ALDH1A1 (0.63) ALDH1A1MEN1KMT2AMAPTKDM4E
SCHEMBL9241499 0.87 MEN1 (0.60) ALDH1A1MEN1KMT2AMAPTKDM4E
Bromide SCHEMBL8664123 0.84 MEN1 (0.94) ALDH1A1MEN1KMT2AMAPTKDM4E
Hydrochloric Acid SCHEMBL11134568 0.84 ALDH1A1 (0.79) ALDH1A1MEN1KMT2AMAPTKDM4E
SCHEMBL8733835 0.81 ALDH1A1 (0.50) ALDH1A1MEN1KMT2AMAPTKDM4E
Bromide SCHEMBL11681833 0.81 KMT2A (0.56) ALDH1A1MEN1KMT2AMAPTKDM4E
Iodide SCHEMBL29278144 0.81 LMNA (0.64) ALDH1A1MEN1KMT2AMAPTKDM4E
Bromide SCHEMBL28605769 0.81 ALDH1A1 (0.61) ALDH1A1MEN1KMT2AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0385504-B1 Heat-latent curing catalyst and resin compositions containing the same NIPPON PAINT CO LTD (JP) 1995-10-04 EP claimed
CN-115160213-B Rheum emodic acid pyridine quaternary ammonium salt compound and synthetic method and application thereof 丽江师范高等专科学校 2024-02-13 CN disclosed
US-20160228356-A1 THE CONTINUOUS LONG-TERM CONTROLLED RELEASE OF TELOMERASE INHIBITORS LASTER, Brenda (IL) 2016-08-11 US disclosed
CN-1246412-C Adhesive for flexible printed circuit board TAIHONG SCIENCE & TECHNOLOGY C (CN) 2006-03-22 CN disclosed
CN-1407049-A Adhesive for flexible printed circuit board TAIHONG SCIENCE & TECHNOLOGY C (CN) 2003-04-02 CN disclosed
EP-0543022-B1 PROCESS FOR PRODUCING STYRENIC POLYMER AND CATALYST THEREFOR IDEMITSU KOSAN CO (JP) 1998-02-04 EP disclosed
US-5391661-A Process for producing a styrenic polymer and a catalyst for use therein IDEMITSU KOSAN CO., LTD. (JP) 1995-02-21 US disclosed
EP-0543022-A1 PROCESS FOR PRODUCING STYRENIC POLYMER AND CATALYST THEREFOR IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-05-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160228356-A1 THE CONTINUOUS LONG-TERM CONTROLLED RELEASE OF TELOMERASE INHIBITORS TERT, POT1, TERF2 ALDH1A1 1296/4885MEN1 895/4885KMT2A 2366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.