Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 8/20 | 0.41 |
| ▸ | CNR2 | P34972 | 8/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | MARS1 | P56192 | 5/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969034 | 0.85 | ALDH1A1 (0.38) | PTGS2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7593441 | 0.85 | ALDH1A1 (0.38) | PTGS2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7984729 | 0.83 | CHRNA1 (0.39) | PTGS2ALDH1A1HPGD | |
| SCHEMBL6026477 | 0.83 | CHRNA1 (0.39) | PTGS2ALDH1A1HPGD | |
| SCHEMBL6026165 | 0.78 | HSD17B1 (0.38) | NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6932927 | 0.76 | CHRNA1 (0.42) | PTGS2NPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL7983353 | 0.76 | CHRNA1 (0.42) | PTGS2NPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL6931685 | 0.74 | PGR (0.43) | PTGS2AHRALDH1A1 | |
| SCHEMBL6934036 | 0.74 | PTGS2 (0.37) | PTGS2NPC1ALDH1A1TSHRRAB9A | |
| SCHEMBL7030070 | 0.74 | HCAR2 (0.46) | PTGS2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |