SCHEMBL7965653

SCHEMBL7965653

CCc1cc(O)cc(C)c1OCCCCNC(=O)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.51
GPR84 Q9NQS5 1/20 0.46
HPGD P15428 2/20 0.46
NPC1 O15118 4/20 0.45
RAB9A P51151 4/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
HDAC3 O15379 2/20 0.45
HDAC4 P56524 2/20 0.45
HDAC1 Q13547 2/20 0.45
HDAC7 Q8WUI4 2/20 0.45
HDAC2 Q92769 2/20 0.45
HDAC10 Q969S8 2/20 0.45
HDAC11 Q96DB2 2/20 0.45
HDAC8 Q9BY41 2/20 0.45
HDAC6 Q9UBN7 2/20 0.45
HDAC9 Q9UKV0 2/20 0.45
HDAC5 Q9UQL6 2/20 0.45
PDE5A O76074 1/20 0.44
LMNA P02545 1/20 0.44
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7978800 0.96 SMN1; SMN2 (0.49) NAAAGPR84HPGDNPC1RAB9A
SCHEMBL7979318 0.89 NPC1 (0.48) NPC1RAB9ASMN1; SMN2HDAC3HDAC4
SCHEMBL7979214 0.87 PPARD (0.48) NPC1RAB9APOLB
SCHEMBL7979168 0.86 NAAA (0.48) NAAAGPR84HPGDNPC1RAB9A
SCHEMBL7975893 0.85 NPC1 (0.52) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL7977604 0.84 EPHX2 (0.50) NPC1RAB9AHDAC3HDAC1HDAC2
SCHEMBL7979330 0.83 PPARD (0.46) HPGDNPC1RAB9APOLBKMT2A
SCHEMBL7965774 0.82 NPC1 (0.49) NAAAGPR84HPGDNPC1RAB9A
SCHEMBL7981831 0.81 HDAC3 (0.49) NPC1RAB9AHDAC3HDAC1HDAC2
SCHEMBL7979207 0.79 GPR84 (0.51) NAAAGPR84HPGDNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6214835-B1 CONTROLLING INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-04-10 US disclosed
EP-0824514-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2000-09-06 EP disclosed
US-6028100-A Dihalopropene compounds, insecticides containing them as active ingredients, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-02-22 US disclosed
US-5952386-A EXCELLENT INSECTICIDAL ACTIVITY FOR THE CONTROL OF NOXIOUS INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-09-14 US disclosed
CN-1187809-A Dihalopropene compound, insecticide containing the same as active ingredient, and production intermediate thereof SUMITOMO CHEMICAL CO (JP) 1998-07-15 CN disclosed
EP-0824514-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-02-25 EP disclosed
WO-1996033160-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-10-24 WO disclosed