SCHEMBL7979168

SCHEMBL7979168

Cc1cc(O)cc(Cl)c1OCCCCNC(=O)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.48
GPR84 Q9NQS5 1/20 0.46
MRGPRX4 Q96LA9 1/20 0.46
HPGD P15428 2/20 0.46
SMN1; SMN2 Q16637 3/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
HDAC3 O15379 2/20 0.45
HDAC4 P56524 2/20 0.45
HDAC1 Q13547 2/20 0.45
HDAC7 Q8WUI4 2/20 0.45
HDAC2 Q92769 2/20 0.45
HDAC10 Q969S8 2/20 0.45
HDAC11 Q96DB2 2/20 0.45
HDAC8 Q9BY41 2/20 0.45
HDAC6 Q9UBN7 2/20 0.45
HDAC9 Q9UKV0 2/20 0.45
HDAC5 Q9UQL6 2/20 0.45
POLB P06746 2/20 0.44
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7965774 0.96 NPC1 (0.49) NAAAGPR84MRGPRX4HPGDSMN1; SMN2
SCHEMBL7979207 0.92 GPR84 (0.51) NAAAGPR84HPGDSMN1; SMN2NPC1
SCHEMBL7979257 0.91 NPC1 (0.50) SMN1; SMN2NPC1RAB9AHDAC3HDAC4
SCHEMBL7979206 0.88 RAB9A (0.55) NAAAGPR84HPGDSMN1; SMN2NPC1
SCHEMBL7981926 0.87 NPC1 (0.54) SMN1; SMN2NPC1RAB9AHDAC3HDAC4
SCHEMBL7965796 0.87 RHOC (0.47) MRGPRX4
SCHEMBL7965653 0.86 NAAA (0.51) NAAAGPR84HPGDSMN1; SMN2NPC1
SCHEMBL7976020 0.84 TRPV1 (0.52) NPC1RAB9AHDAC3HDAC1HDAC2
SCHEMBL7965640 0.83 RHOC (0.51) MRGPRX4NPC1
SCHEMBL7978800 0.82 SMN1; SMN2 (0.49) NAAAGPR84HPGDSMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6214835-B1 CONTROLLING INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-04-10 US disclosed
EP-0824514-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2000-09-06 EP disclosed
US-6028100-A Dihalopropene compounds, insecticides containing them as active ingredients, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-02-22 US disclosed
US-5952386-A EXCELLENT INSECTICIDAL ACTIVITY FOR THE CONTROL OF NOXIOUS INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-09-14 US disclosed
CN-1187809-A Dihalopropene compound, insecticide containing the same as active ingredient, and production intermediate thereof SUMITOMO CHEMICAL CO (JP) 1998-07-15 CN disclosed
EP-0824514-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-02-25 EP disclosed
WO-1996033160-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-10-24 WO disclosed