Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 6/20 | 0.40 |
| ▸ | PTAFR | P25105 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966646 | 1.00 | CYP11B1 (0.45) | CYP11B1CYP11B2ALDH1A1HTTKMT2A | |
| SCHEMBL7966718 | 0.90 | PDK1 (0.50) | CYP11B1CYP11B2ALDH1A1HTTKMT2A | |
| SCHEMBL7978375 | 0.90 | PDK1 (0.50) | CYP11B1CYP11B2ALDH1A1HTTKMT2A | |
| SCHEMBL7980152 | 0.85 | MARS1 (0.46) | LMNAPDK1PTAFRPOLBHPGD | |
| SCHEMBL7979921 | 0.85 | PDK1 (0.39) | CYP11B1CYP11B2HTTPDK1PTAFR | |
| SCHEMBL7976682 | 0.80 | NAMPT (0.46) | HTTKMT2AMEN1LMNAPTAFR | |
| SCHEMBL8022091 | 0.80 | NAMPT (0.46) | HTTKMT2AMEN1LMNAPTAFR | |
| SCHEMBL7976678 | 0.80 | NAMPT (0.46) | HTTKMT2AMEN1LMNAPTAFR | |
| SCHEMBL7979927 | 0.79 | NAMPT (0.49) | HTTKMT2AMAPTMEN1LMNA | |
| SCHEMBL7978580 | 0.79 | NAMPT (0.49) | HTTKMT2AMAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300352-B1 | FOR THERAPY OF ASTHMA | ASTRAZENECA AB (SE) | 2001-10-09 | — | — | US | claimed |
| US-6300352-B1 | FOR THERAPY OF ASTHMA | ASTRAZENECA AB (SE) | 2001-10-09 | — | — | US | disclosed |