Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 10/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | KLK1 | P06870 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.34 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.34 |
| ▸ | PLA2G2E | Q9NZK7 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.34 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966714 | 0.85 | PLA2G2A (0.45) | ADRA1DPLA2G2APLA2G1BPLA2G10PLA2G5 | |
| SCHEMBL7966710 | 0.84 | ADRA1D (0.42) | ADRA1DPPARGPLA2G2APLA2G1BGRM2 | |
| SCHEMBL27526243 | 0.81 | ADRA1D (0.44) | ADRA1DPPARGPLA2G2AGRM2PLA2G10 | |
| SCHEMBL30410966 | 0.78 | ADRA1D (0.46) | ADRA1DPLA2G2APLA2G1BKLK1 | |
| SCHEMBL29029780 | 0.78 | ADRA1D (0.46) | ADRA1DPLA2G2APLA2G1BKLK1 | |
| SCHEMBL27526247 | 0.77 | ADRA1D (0.48) | ADRA1DPPARGPLA2G2AGRM2PLA2G10 | |
| SCHEMBL27507593 | 0.76 | ADRA1D (0.45) | ADRA1DPPARGPLA2G2AGRM2KLK1 | |
| SCHEMBL6129596 | 0.76 | PPARG (0.45) | PPARGPLA2G2APLA2G1BPLA2G10PLA2G5 | |
| SCHEMBL8575180 | 0.76 | PLA2G2A (0.46) | ADRA1DPLA2G2APLA2G1BPLA2G10PLA2G5 | |
| SCHEMBL27526153 | 0.76 | ADRA1D (0.44) | ADRA1DPPARGPLA2G2APLA2G1BGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177440-B1 | THERAPY FOR SEPSIS SHOCK; PHOSPHOLIPASE INHBITOR | ELI LILLY AND COMPANY | 2001-01-23 | — | — | US | disclosed |