Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 4/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 8/20 | 0.33 |
| ▸ | PLA2G2D | Q9UNK4 | 2/20 | 0.33 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.32 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.32 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966714 | 0.87 | PLA2G2A (0.45) | ADRA1DPLA2G10PLA2G2APLA2G2DPLA2G5 | |
| SCHEMBL7966708 | 0.84 | ADRA1D (0.44) | ADRA1DGRM2PLA2G10PPARGPLA2G2A | |
| SCHEMBL27526243 | 0.78 | ADRA1D (0.44) | ADRA1DGRM2PLA2G10PPARGPLA2G2A | |
| SCHEMBL6129597 | 0.78 | PPARG (0.43) | PLA2G10PPARGPLA2G2APLA2G2DPLA2G5 | |
| SCHEMBL6534810 | 0.77 | PLA2G2A (0.39) | PLA2G10PLA2G2APLA2G2DPLA2G5PLA2G2F | |
| SCHEMBL7968908 | 0.77 | CTNNB1 (0.39) | PLA2G10PLA2G2APLA2G5PLA2G1B | |
| SCHEMBL6129602 | 0.77 | PLA2G2A (0.41) | PLA2G10PLA2G2APLA2G2DPLA2G5PLA2G2F | |
| SCHEMBL6129648 | 0.77 | PLA2G2A (0.46) | PLA2G10PLA2G2A | |
| SCHEMBL6129642 | 0.77 | PLA2G2A (0.41) | PLA2G10PLA2G2APLA2G2DPLA2G5PLA2G2F | |
| SCHEMBL8575181 | 0.77 | PLA2G2A (0.46) | PLA2G10PLA2G2APLA2G2DPLA2G5PLA2G2F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177440-B1 | THERAPY FOR SEPSIS SHOCK; PHOSPHOLIPASE INHBITOR | ELI LILLY AND COMPANY | 2001-01-23 | — | — | US | disclosed |