Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 9/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968911 | 0.88 | PLA2G2A (0.45) | CTNNB1PLA2G2APLA2G1BPLA2G10PLA2G5 | |
| SCHEMBL7968907 | 0.86 | CTNNB1 (0.41) | CTNNB1SYKPLA2G2APLA2G1BPLA2G10 | |
| SCHEMBL27530208 | 0.80 | CTNNB1 (0.40) | CTNNB1SCN9ASYKPLA2G2APLA2G1B | |
| SCHEMBL6773208 | 0.80 | CTNNB1 (0.42) | CTNNB1PLA2G2APLA2G1BPLA2G10PLA2G5 | |
| SCHEMBL7963737 | 0.80 | PLA2G2A (0.47) | PLA2G2APLA2G1BPLA2G10PLA2G5 | |
| SCHEMBL6774146 | 0.79 | CTNNB1 (0.49) | CTNNB1SCN9ASYKPLA2G2APLA2G1B | |
| SCHEMBL8575181 | 0.79 | PLA2G2A (0.46) | PLA2G2APLA2G1BPLA2G10PLA2G5 | |
| SCHEMBL7966738 | 0.78 | PLA2G2A (0.52) | CTNNB1PLA2G2APLA2G1BPLA2G10PLA2G5 | |
| SCHEMBL6776025 | 0.78 | CTNNB1 (0.43) | CTNNB1SYKPLA2G2APLA2G1BPLA2G10 | |
| SCHEMBL7966710 | 0.77 | ADRA1D (0.42) | PLA2G2APLA2G1BPLA2G10PLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177440-B1 | THERAPY FOR SEPSIS SHOCK; PHOSPHOLIPASE INHBITOR | ELI LILLY AND COMPANY | 2001-01-23 | — | — | US | disclosed |