Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966021 | 0.86 | HTR1A (0.47) | HTR1ASLC6A4 | |
| SCHEMBL7966964 | 0.83 | HTR1A (0.65) | HTR1ASLC6A4 | |
| SCHEMBL7962234 | 0.82 | HTR1A (0.36) | HTR1ASLC6A4 | |
| SCHEMBL7966960 | 0.81 | HTR1A (0.46) | HTR1ASLC6A4 | |
| SCHEMBL7964964 | 0.81 | HTR1A (0.47) | HTR1ASLC6A4 | |
| SCHEMBL7965932 | 0.79 | HTR1A (0.42) | HTR1ASLC6A4 | |
| SCHEMBL7953373 | 0.77 | HTR1A (0.40) | HTR1ASLC6A4 | |
| SCHEMBL7965744 | 0.71 | HTR1A (0.36) | HTR1ASLC6A4 | |
| SCHEMBL7965634 | 0.70 | HTR1A (0.47) | HTR1ASLC6A4 | |
| SCHEMBL7962233 | 0.70 | HTR1A (0.47) | HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| WO-2000006082-A2 | TREATMENT OF ANXIETY DISORDERS | ELI LILLY AND COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
| WO-2000006166-A1 | 5-HT1F ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0976747-A2 | Use of 5HT-1F receptor antagonists for treating anxiety disorders | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |