Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.37 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22002234 | 0.74 | P2RX7 (0.48) | EPHX2KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL7979165 | 0.72 | EPHX2 (0.62) | EPHX2TSHR | |
| SCHEMBL16884317 | 0.72 | CNR2 (0.51) | HDAC6ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL7980459 | 0.71 | EPHX2 (0.58) | EPHX2ALDH1A1TSHR | |
| SCHEMBL11447009 | 0.71 | POLB (0.53) | EPHX2JAK2JAK1JAK3ALDH1A1 | |
| SCHEMBL30940183 | 0.71 | EPHX2 (0.42) | EPHX2HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL138594 | 0.70 | EPHX2 (0.56) | EPHX2ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL27845477 | 0.68 | EPHX2 (0.54) | EPHX2ALDH1A1TSHR | |
| SCHEMBL9084932 | 0.68 | TSHR (0.53) | EPHX2HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL31247563 | 0.68 | KCNQ3 (0.36) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001074778-A1 | (1-ADAMANTYLAMINO)PYRIDINES AND METHOD OF THEIR PREPARATION | FUNDACJA ROZWOJU DIAGNOSTYKI I TERAPII (PL) | 2001-10-11 | — | — | WO | disclosed |