Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.62 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980459 | 0.78 | EPHX2 (0.58) | EPHX2P2RX7MEN1KMT2ATSHR | |
| SCHEMBL138594 | 0.77 | EPHX2 (0.56) | EPHX2P2RX7TSHRMAPK1NPSR1 | |
| Hydrochloric Acid SCHEMBL27845477 | 0.76 | EPHX2 (0.54) | EPHX2P2RX7MEN1KMT2ATSHR | |
| SCHEMBL19198145 | 0.76 | MEN1 (0.62) | EPHX2P2RX7USP2MEN1KMT2A | |
| SCHEMBL3323740 | 0.73 | P2RX7 (0.75) | EPHX2P2RX7USP2MEN1KMT2A | |
| SCHEMBL7967017 | 0.72 | EPHX2 (0.42) | EPHX2TSHR | |
| SCHEMBL3360289 | 0.72 | CYP17A1 (0.60) | EPHX2P2RX7MEN1KMT2ATSHR | |
| SCHEMBL28345309 | 0.70 | EPHX2 (0.49) | EPHX2P2RX7USP2MEN1KMT2A | |
| SCHEMBL23902890 | 0.70 | TSHR (1.00) | EPHX2USP2MEN1KMT2ATSHR | |
| SCHEMBL1397748 | 0.69 | EPHX2 (0.47) | EPHX2P2RX7TSHRMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001074778-A1 | (1-ADAMANTYLAMINO)PYRIDINES AND METHOD OF THEIR PREPARATION | FUNDACJA ROZWOJU DIAGNOSTYKI I TERAPII (PL) | 2001-10-11 | — | — | WO | claimed |
| WO-2001074778-A1 | (1-ADAMANTYLAMINO)PYRIDINES AND METHOD OF THEIR PREPARATION | FUNDACJA ROZWOJU DIAGNOSTYKI I TERAPII (PL) | 2001-10-11 | — | — | WO | disclosed |