Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | HTR1A | P08908 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966170 | 0.77 | HSD17B10 (0.43) | IKBKBSLC6A2SLC6A4HTR1ASLC6A3 | |
| Hydrochloric Acid SCHEMBL28834350 | 0.75 | MEN1 (0.58) | MEN1KMT2ANPC1RAB9AIKBKB | |
| SCHEMBL7969690 | 0.73 | MEN1 (0.56) | MEN1KMT2ANPC1RAB9ASLC6A2 | |
| SCHEMBL7963691 | 0.72 | JUND (0.41) | IKBKBSLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL7966615 | 0.72 | LMNA (0.46) | IKBKBSLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL5038688 | 0.71 | ALDH1A1 (0.48) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL9306062 | 0.71 | ALDH1A1 (0.59) | MEN1KMT2ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL30967515 | 0.71 | ALDH1A1 (0.48) | MEN1KMT2ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL7966174 | 0.71 | PARP1 (0.54) | IKBKBHSD17B10 | |
| SCHEMBL7057168 | 0.70 | HSP90AA1 (0.54) | MEN1KMT2ANPC1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303627-B1 | FOR THERAPY OF PHYSIOLOGICAL AND PSYCHOLOGICAL DISORDERS | ELI LILLY AND COMPANY | 2001-10-16 | — | — | US | disclosed |
| WO-1999065487-A1 | INHIBITORS OF SEROTONIN REUPTAKE | ELI LILLY AND COMPANY (US) | 1999-12-23 | — | — | WO | disclosed |
| EP-0965587-A1 | Tetrahydropyridinyl- and piperidinyl Inhibitors of serotonin reuptake | ELI LILLY AND COMPANY (US) | 1999-12-22 | — | — | EP | disclosed |