Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7967268

CCCCCCN1CCN(CCCCCC)C1F.O=C(O)C(F)(F)F

nearest known ligand 0.41

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FAAH O00519 8/20 0.41
CES1 P23141 5/20 0.41
CES2 O00748 5/20 0.41
MEN1 O00255 1/20 0.41
CYP1A2 P05177 1/20 0.41
KMT2A Q03164 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CPB2 Q96IY4 1/20 0.39
GBA1 P04062 1/20 0.38
EPHX1 P07099 1/20 0.38
S1PR4 O95977 1/20 0.38
S1PR1 P21453 1/20 0.38
S1PR3 Q99500 1/20 0.38
S1PR5 Q9H228 1/20 0.38
KCNH2 Q12809 1/20 0.37
GNAI3 P08754 1/20 0.37
GNAO1 P09471 1/20 0.37
GNAI1 P63096 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7970743 0.98 CPB2 (0.39) FAAHCES1CES2MEN1CYP1A2
Trifluoroacetic Acid SCHEMBL7973677 0.93 FAAH (0.36) FAAHCES1CES2MEN1CYP1A2
Trifluoroacetic Acid SCHEMBL7967443 0.86 DRD2 (0.42) FAAHCPB2GBA1
Hydrochloric Acid SCHEMBL7216913 0.82 GNAI3 (0.50) GBA1GNAI3GNAO1GNAI1
Bromide SCHEMBL4651634 0.82 GNAI3 (0.46) GBA1GNAI3GNAO1GNAI1
Iodide SCHEMBL7216931 0.82 GNAI3 (0.46) GBA1GNAI3GNAO1GNAI1
Iodide SCHEMBL7246572 0.80 GNAI3 (0.42) GBA1GNAI3GNAO1GNAI1
Bromide SCHEMBL4651690 0.80 GNAI3 (0.42) GBA1GNAI3GNAO1GNAI1
Hydrochloric Acid SCHEMBL7224340 0.80 GNAI3 (0.47) GBA1GNAI3GNAO1GNAI1
Trifluoroacetic Acid SCHEMBL7957545 0.79 DPP7 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6222046-B1 AS TRIFLUOROACETOXYLATION AGENT MITSUI CHEMICALS, INC. (JP) 2001-04-24 US disclosed
EP-0982299-A1 Tetraalkylfluoroformamidinium trifluoroacetate and its use as trifluoroacetoxylation agent Mitsui Chemicals, Inc. (JP) 2000-03-01 EP disclosed