Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PTGIR | P43119 | 9/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 7/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958975 | 0.74 | KDM4E (0.46) | ADORA2AADORA3ADORA1KDM4EALDH1A1 | |
| SCHEMBL7948818 | 0.74 | KDM4E (0.45) | MAPTADORA2AADORA3ADORA1KDM4E | |
| SCHEMBL7956256 | 0.72 | PTGIR (0.45) | ADORA2AADORA3ADORA1KDM4EALDH1A1 | |
| SCHEMBL4516388 | 0.70 | ADORA3 (0.41) | MAPTMEN1KMT2AADORA2AADORA3 | |
| SCHEMBL4516383 | 0.70 | ADORA3 (0.41) | MAPTMEN1KMT2AADORA2AADORA3 | |
| SCHEMBL4516375 | 0.70 | ADORA3 (0.41) | MAPTMEN1KMT2AADORA2AADORA3 | |
| SCHEMBL7958318 | 0.70 | PTGIR (0.43) | ADORA2AADORA3ADORA1KDM4EALDH1A1 | |
| SCHEMBL10507560 | 0.70 | ALDH1A1 (0.49) | MEN1KMT2AADORA2AADORA3ADORA1 | |
| SCHEMBL7958971 | 0.70 | ALDH1A1 (0.49) | MEN1KMT2AADORA2AADORA3ADORA1 | |
| SCHEMBL7956745 | 0.69 | PTGIR (0.47) | ADORA2AADORA3ADORA1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |