Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 8/20 | 0.43 |
| ▸ | PTGIR | P43119 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962574 | 0.79 | ADORA2A (0.42) | KDM4EADORA3ADORA2AADORA1SMN1; SMN2 | |
| SCHEMBL7958324 | 0.78 | ADORA3 (0.43) | ALDH1A1KDM4EHPGDTDP1ADORA3 | |
| SCHEMBL7948741 | 0.74 | PTGIR (0.58) | ALDH1A1KDM4EHPGDTDP1SMN1; SMN2 | |
| SCHEMBL10507560 | 0.70 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDTDP1ADORA3 | |
| SCHEMBL7967332 | 0.70 | MAPT (0.48) | ALDH1A1KDM4EHPGDTDP1ADORA3 | |
| SCHEMBL7948818 | 0.69 | KDM4E (0.45) | ALDH1A1KDM4EHPGDTDP1ADORA3 | |
| SCHEMBL18173680 | 0.68 | KMT2A (0.56) | ALDH1A1KDM4EADORA2AADORA1SMN1; SMN2 | |
| SCHEMBL18173682 | 0.68 | KMT2A (0.56) | ALDH1A1KDM4EADORA2AADORA1SMN1; SMN2 | |
| SCHEMBL10375101 | 0.68 | ADORA3 (0.53) | ALDH1A1KDM4EHPGDTDP1ADORA3 | |
| Naphthyloxyacetic Acid SCHEMBL120838 | 0.68 | KDM4E (1.00) | ALDH1A1KDM4EHPGDTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| US-6043264-A | A THROMBOXANE A2 RECEPTOR ANTAGONIST FOR TREATING HYPERTENSION, THROMBOSIS, ISCHEMIC HEART DISEASES, CIRCULATORY DISEASES, ARTERIOSCLEROSIS, PLATELET FUNCTION DISORDER, HYPERLIPIDEMIA, NEPHRITIS OR ASTHMA | TORAY INDUSTRIES, INC. (JP) | 2000-03-28 | — | — | US | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |