Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL7967347 | 0.75 | DRD4 (0.53) | DRD2KDM4EPRMT5 | |
| Maleic Acid SCHEMBL7967346 | 0.73 | RAB9A (0.42) | CHRNB2CHRNA7CHRNA4HRH1HRH3 | |
| Fumaric Acid SCHEMBL7967350 | 0.73 | RAB9A (0.42) | CHRNB2CHRNA7CHRNA4HRH1HRH3 | |
| Bromide SCHEMBL7953920 | 0.70 | MAOB (0.43) | MAOBMAOADRD2SLC6A4HRH3 | |
| SCHEMBL7966021 | 0.68 | HTR1A (0.47) | SLC6A4HTR1A | |
| SCHEMBL9456721 | 0.68 | HTR3A (0.56) | DRD2SLC6A4KDM4EPRMT5 | |
| SCHEMBL8142150 | 0.68 | KDM4E (0.47) | CHRNB2CHRNA7CHRNA4SLC6A4RAB9A | |
| SCHEMBL7963780 | 0.67 | AKT1 (0.37) | HRH1DRD2RAB9AKMT2A | |
| SCHEMBL9456766 | 0.67 | PLD1 (0.58) | DRD2HTR1A | |
| Bromide SCHEMBL9323877 | 0.67 | HTR3A (0.55) | DRD2SLC6A4KDM4EPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |