Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 3/20 | 0.37 |
| ▸ | LIG1 | P18858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958239 | 0.77 | LMNA (0.40) | ALOX5KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL13672076 | 0.76 | KDM4E (0.38) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30659408 | 0.76 | PDK2 (0.38) | KDM4EALDH1A1SMN1; SMN2BRD4CREBBP | |
| SCHEMBL16792465 | 0.76 | PDK2 (0.38) | KDM4EALDH1A1SMN1; SMN2BRD4CREBBP | |
| SCHEMBL3601425 | 0.76 | PDK2 (0.38) | KDM4EALDH1A1SMN1; SMN2BRD4MAPT | |
| SCHEMBL4483899 | 0.76 | PDK2 (0.38) | KDM4EALDH1A1SMN1; SMN2BRD4CREBBP | |
| SCHEMBL14444683 | 0.76 | BRD4 (0.38) | KDM4EALDH1A1SMN1; SMN2BRD4CREBBP | |
| SCHEMBL10556439 | 0.74 | ALOX5 (0.53) | ALOX5KDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL21818563 | 0.74 | ALOX5 (0.40) | ALOX5KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL4968292 | 0.73 | DRD2 (0.36) | KDM4EALDH1A1SMN1; SMN2BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009127-A1 | BENZOXAZINE DERIVATIVES AND THEIR THERAPEUTIC USE | AVENTIS PHARMA S.A. (FR) | 2001-02-08 | — | — | WO | disclosed |