Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.89 |
| ▸ | ATM | Q13315 | 1/20 | 0.89 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.71 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.71 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.71 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.71 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.71 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.71 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.71 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.71 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.71 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.71 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.71 |
| ▸ | F3 | P13726 | 2/20 | 0.68 |
| ▸ | GSK3B | P49841 | 2/20 | 0.64 |
| ▸ | BACE1 | P56817 | 1/20 | 0.63 |
| ▸ | BCHE | P06276 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7967986 | 1.00 | THRB (0.89) | THRBATMHDAC8HDAC6HDAC3 | |
| SCHEMBL12473720 | 1.00 | THRB (0.89) | THRBATMHDAC8HDAC6HDAC3 | |
| 4-Methoxycinnamic Acid SCHEMBL58700 | 0.94 | THRB (1.00) | THRBATMHDAC8HDAC6HDAC3 | |
| 4-Methoxycinnamic Acid SCHEMBL12473722 | 0.94 | THRB (1.00) | THRBATMHDAC8HDAC6HDAC3 | |
| 4-Methoxycinnamic Acid SCHEMBL58699 | 0.94 | THRB (1.00) | THRBATMHDAC8HDAC6HDAC3 | |
| 4-Methoxycinnamic Acid SCHEMBL10935651 | 0.93 | THRB (0.96) | THRBATMHDAC8HDAC6HDAC3 | |
| 4-Methoxycinnamic Acid SCHEMBL8500105 | 0.93 | THRB (0.96) | THRBATMHDAC8HDAC6HDAC3 | |
| 4-Methoxycinnamic Acid SCHEMBL5330605 | 0.93 | THRB (0.96) | THRBATMHDAC8HDAC6HDAC3 | |
| 4-Methoxycinnamic Acid SCHEMBL4654596 | 0.93 | THRB (0.96) | THRBATMHDAC8HDAC6HDAC3 | |
| 4-Methoxycinnamic Acid SCHEMBL5330596 | 0.93 | THRB (0.96) | THRBATMHDAC8HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595952-B1 | AGONISTS OF GPR40 | CONNEXIOS LIFE SCIENCES PVT LTD (IN) | 2020-11-18 | — | — | EP | disclosed |
| US-9278915-B2 | Agonists of GPR40 | CONNEXIOS LIFE SCIENCES PVT LTD (IN) | 2016-03-08 | — | — | US | disclosed |
| US-20130237571-A1 | AGONISTS OF GPR40 | Conexios Life Sciences PVT. LTD. (IN) | 2013-09-12 | — | — | US | disclosed |
| EP-2595952-A1 | AGONISTS OF GPR40 | Connexios Life Sciences Pvt. Ltd. (IN) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012011125-A1 | AGONISTS OF GPR40 | CONNEXIOS LIFE SCIENCES PVT. LTD. (IN) | 2012-01-26 | — | — | WO | disclosed |
| US-6277502-B1 | ORGANOSILICON POLYMERS; LIQUID CRYSALS | ROLIC AG (CH) | 2001-08-21 | — | — | US | disclosed |
| US-5139696-A | Hydrogen-bonded liquid crystal complexes | CORNELL RESEARCH FOUNDATION, INC. (US) | 1992-08-18 | — | — | US | disclosed |
| US-5037574-A | Hydrogen-bonded liquid crystal complexes | CORNELL RESEARCH FOUNDATION, INC. (US) | 1991-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130237571-A1 | AGONISTS OF GPR40 | GPR65, GPR55, GPR68 | THRB 489/4885ATM 4366/4885HDAC8 1591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.