Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 9/20 | 0.55 |
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | NPC1 | O15118 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.51 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977687 | 0.91 | ALOX5 (0.61) | ALOX5RAB9AMAPTNPC1MEN1 | |
| SCHEMBL7981755 | 0.90 | MAPT (0.64) | ALOX5SMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL7967444 | 0.85 | MAPT (0.47) | ALOX5SMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL7968301 | 0.79 | ALOX5 (0.54) | ALOX5RAB9AMAPTNPC1MEN1 | |
| SCHEMBL7979370 | 0.78 | KDR (0.63) | HDAC6VCP | |
| SCHEMBL1822611 | 0.77 | SMN1; SMN2 (0.84) | ALOX5SMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL22560266 | 0.77 | RAB9A (0.73) | ALOX5SMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL23742626 | 0.76 | CYP1A1 (0.88) | ALOX5SMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL4742547 | 0.76 | ALOX5 (1.00) | ALOX5SMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL6798095 | 0.76 | ALOX5 (0.71) | ALOX5SMN1; SMN2RAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001087845-A2 | N-CONTAINING HETEROCYCLIC COMPOUNDS AND THEIR USE AS 5-HT ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-22 | — | — | WO | disclosed |