Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981755 | 0.84 | MAPT (0.64) | ALOX5PTGS2MEN1KMT2AMAPT | |
| SCHEMBL7977687 | 0.83 | ALOX5 (0.61) | ALOX5PTGS2MEN1KMT2AMAPT | |
| SCHEMBL7968277 | 0.79 | ALOX5 (0.60) | ALOX5PTGS2MEN1KMT2APOLB | |
| SCHEMBL3640947 | 0.79 | PSEN1 (0.62) | ALOX5PTGS2MEN1KMT2AMAPT | |
| SCHEMBL7967444 | 0.78 | MAPT (0.47) | ALOX5PTGS2MEN1KMT2AMAPT | |
| SCHEMBL7129752 | 0.75 | PSEN1 (0.62) | ALOX5PTGS2MEN1KMT2APOLB | |
| SCHEMBL12297174 | 0.75 | VCP (0.65) | ALOX5PTGS2MEN1KMT2AMAPT | |
| Bromide SCHEMBL7129762 | 0.74 | PSEN1 (0.61) | ALOX5PTGS2MEN1KMT2APOLB | |
| SCHEMBL12298012 | 0.72 | KMT2A (0.64) | PTGS2MEN1KMT2APOLBMAPT | |
| SCHEMBL3634967 | 0.72 | ALOX5 (0.55) | ALOX5PTGS2MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001087845-A2 | N-CONTAINING HETEROCYCLIC COMPOUNDS AND THEIR USE AS 5-HT ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-22 | — | — | WO | disclosed |