Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.36 |
| ▸ | GALR1 | P47211 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6028406 | 0.86 | FPR2 (0.35) | NOTUMS1PR1DHODHHDAC4HDAC2 | |
| SCHEMBL7968628 | 0.83 | — | — | |
| SCHEMBL7972402 | 0.83 | MMP12 (0.32) | — | |
| SCHEMBL7968985 | 0.81 | NOTUM (0.39) | NOTUMHSP90AA1GAAMAPTKMT2A | |
| SCHEMBL7971888 | 0.81 | DHODH (0.40) | NOTUMHSP90AA1GAAMAPTKMT2A | |
| SCHEMBL6932927 | 0.79 | CHRNA1 (0.42) | MAPTKMT2AACMSDNPC1RAB9A | |
| SCHEMBL7983353 | 0.79 | CHRNA1 (0.42) | MAPTKMT2AACMSDNPC1RAB9A | |
| SCHEMBL7984718 | 0.79 | CHRNA1 (0.42) | MAPTKMT2AACMSDNPC1RAB9A | |
| SCHEMBL6026628 | 0.78 | MEN1 (0.37) | NOTUMKMT2ANPC1RAB9A | |
| SCHEMBL7969034 | 0.76 | ALDH1A1 (0.38) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |