Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | GALR1 | P47211 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956141 | 0.86 | HSD11B1 (0.37) | TDP1HDAC2 | |
| SCHEMBL7968466 | 0.81 | NOTUM (0.39) | NOTUMACMSDCYP3A4HSP90AA1GAA | |
| SCHEMBL7971888 | 0.80 | DHODH (0.40) | NOTUMACMSDCYP3A4HSP90AA1GAA | |
| SCHEMBL7968980 | 0.71 | PTGER3 (0.35) | GAAKMT2ANPC1RAB9AS1PR1 | |
| SCHEMBL6934430 | 0.71 | AKR1C2 (0.36) | KMT2ANPC1RAB9AS1PR1 | |
| SCHEMBL6028406 | 0.69 | FPR2 (0.35) | NOTUMDHODHHDAC4HDAC2HDAC8 | |
| SCHEMBL6026778 | 0.69 | BACE1 (0.36) | NPC1RAB9A | |
| SCHEMBL7966819 | 0.68 | HSP90AA1 (0.42) | NOTUMACMSDHSP90AA1GAAMAPT | |
| Hydrogen Peroxide SCHEMBL28451101 | 0.67 | NPC1 (0.52) | NOTUMACMSDCYP3A4HSP90AA1GAA | |
| SCHEMBL59138 | 0.67 | NOTUM (0.55) | NOTUMACMSDHSP90AA1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |