6-Mercaptonicotinic Acid

6-Mercaptonicotinic Acid

SCHEMBL796849

O=C(O)c1ccc(S)nc1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 1/20 0.63
GABRD O14764 1/20 0.63
GABRA1 P14867 1/20 0.63
GABRB1 P18505 1/20 0.63
GABRG2 P18507 1/20 0.63
GABRB3 P28472 1/20 0.63
GABRA5 P31644 1/20 0.63
GABRA3 P34903 1/20 0.63
GABRA2 P47869 1/20 0.63
GABRB2 P47870 1/20 0.63
GABRA4 P48169 1/20 0.63
GABRE P78334 1/20 0.63
GABRA6 Q16445 1/20 0.63
GABRG1 Q8N1C3 1/20 0.63
GABRG3 Q99928 1/20 0.63
GABRQ Q9UN88 1/20 0.63
P4HA1 P13674 3/20 0.61
P4HTM Q9NXG6 2/20 0.61
MIF P14174 1/20 0.59
NAPRT Q6XQN6 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
6-Mercaptonicotinic Acid SCHEMBL31589674 1.00 GABRP (0.63) GABRPGABRDGABRA1GABRB1GABRG2
6-Mercaptonicotinic Acid SCHEMBL27863095 0.98 GABRP (0.61) GABRPGABRDGABRA1GABRB1GABRG2
6-Mercaptonicotinic Acid SCHEMBL7484954 0.83 ALDH1A1 (0.47) GABRPGABRDGABRA1GABRB1GABRG2
6-Mercaptonicotinic Acid SCHEMBL6809889 0.82 GABRP (0.45) GABRPGABRDGABRA1GABRB1GABRG2
6-Mercaptonicotinic Acid SCHEMBL11567232 0.80 GABRP (0.44) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL30004108 0.80 KCNJ1 (0.46) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL8184672 0.80 KCNJ1 (0.46) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL1647540 0.80 NNMT (0.67) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL29530489 0.77 GABRP (1.00) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL42011 0.77 GABRP (1.00) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 359 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12584860-B1 Undercoat corrosion monitoring Raman sensor TDA RESEARCH, INC. (US) 2026-03-24 US claimed
US-20250198037-A1 GOLD ELECTROPLATING SOLUTION AND ITS USE FOR ELECTRODEPOSITING GOLD WITH AN AGED APPEARANCE Université de Franche-Comté (FR) 2025-06-19 US claimed
CN-120037973-A Preparation method of sulfhydryl grafted sponge structure biochar for removing new pollutants 上海交通大学 2025-05-27 CN claimed
EP-4493743-A1 GOLD ELECTROPLATING SOLUTION AND ITS USE FOR ELECTRODEPOSITING GOLD WITH AN AGED APPEARANCE Université de Franche-Comté (FR) 2025-01-22 EP claimed
CN-118019523-A Mucoadhesive ocular delivery system for the treatment of glaucoma 生物粘附眼科公司 2024-05-10 CN claimed
CN-117487181-A Preparation of nickel-calcium coordination polymer and application of nickel-calcium coordination polymer in photocatalytic hydrogen production 福州大学 2024-02-02 CN claimed
US-11845891-B2 Chemical synthesis of hybrid inorganic-organic nanostructured corrosion inhibitive pigments and methods RTX CORPORATION (US) 2023-12-19 US claimed
CN-116804124-A Leveling agent for hot-melt road marking paint and preparation method thereof 宁波职业技术学院 2023-09-26 CN claimed
WO-2023174871-A1 GOLD ELECTROPLATING SOLUTION AND ITS USE FOR ELECTRODEPOSITING GOLD WITH AN AGED APPEARANCE Université de Franche-Comté (FR) 2023-09-21 WO claimed
EP-4245893-A1 GOLD ELECTROPLATING SOLUTION AND ITS USE FOR ELECTRODEPOSITING GOLD WITH AN AGED APPEARANCE Université de Franche-Comté (FR) 2023-09-20 EP claimed
US-6515122-B1 The invention further relates to combinatorial libraries containing two or more such compounds, as well as methods of preparing tetracyclic benzimidazole derivative compounds. LION BIOSCIENCE AG (DE) 2003-02-04 US claimed
EP-1218384-A4 TETRACYCLIC BENZIMIDAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2002-11-20 EP claimed
EP-1218384-A1 TETRACYCLIC BENZIMIDAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION Bioscience AG (DE) 2002-07-03 EP claimed
WO-2001023392-A1 TETRACYCLIC BENZIMIDAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2001-04-05 WO claimed
US-5334384-A Treating the protein mixture with reducing agent to reduce disulfide bridge to free thiol group, which reacts with a reagent, separating modified protein impurity by filtration, sedimentation, centrifuging or retention within chromatography BEECHAM GROUP P.L.C. (GB) 1994-08-02 US claimed
EP-0365278-B1 Protein purification process BEECHAM GROUP PLC (GB) 1994-03-30 EP claimed
US-5094957-A In aqueous systems ROHM AND HAAS COMPANY (US) 1992-03-10 US claimed
EP-0365278-A2 Protein purification process BEECHAM GROUP PLC (GB) 1990-04-25 EP claimed
US-4764520-A 6-MERCAPTONICOTINIC ACID AND SALTS ZACKHEIM, HERSCHEL S. 1/2% 1988-08-16 US claimed
US-4521425-A 6-MERCAPTONICOTINIC ACID TO REDUCE BLOOD CORTISOL LEVEL GRASSETTI DAVIDE R 1985-06-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584860-B1 Undercoat corrosion monitoring Raman sensor CD44, SULT1E1, RCOR1 GABRP 2101/4885GABRD 1959/4885GABRA1 1372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.