Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.45 |
| ▸ | GABRE | P78334 | 1/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.45 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 6-Mercaptonicotinic Acid SCHEMBL796849 | 0.82 | GABRP (0.63) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| 6-Mercaptonicotinic Acid SCHEMBL31589674 | 0.82 | GABRP (0.63) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| 6-Mercaptonicotinic Acid SCHEMBL27863095 | 0.80 | GABRP (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL133541 | 0.70 | — | — | |
| SCHEMBL2103664 | 0.70 | — | — | |
| SCHEMBL2259011 | 0.68 | HCAR3 (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| 6-Mercaptonicotinic Acid SCHEMBL7484954 | 0.68 | ALDH1A1 (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11582606 | 0.68 | FOLH1 (0.52) | ALDH1A1CYP2C9HPGDHSD17B10MAPT | |
| SCHEMBL7899825 | 0.68 | FOLH1 (0.52) | ALDH1A1CYP2C9HPGDHSD17B10MAPT | |
| SCHEMBL11410952 | 0.68 | FOLH1 (0.52) | ALDH1A1CYP2C9HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040018983-A1 | Antifungal compositions | ACHILLION PHARMACEUTICALS, INC. | 2004-01-29 | — | — | US | claimed |
| WO-2003055448-A2 | ANTIFUNGAL COMPOSITIONS | ACHILLION PHARMACEUTICALS, INC. (US) | 2003-07-10 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040018983-A1 | Antifungal compositions | CNBP, ERG28, AEBP2 | GABRP 2233/4885GABRD 2380/4885GABRA1 3370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.