Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RARB | P10826 | 2/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 3/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975157 | 0.93 | RARB (0.40) | MAPTRARBRARAALPLKDM4E | |
| SCHEMBL7928473 | 0.91 | ALPL (0.43) | MAPTRARBRARAGAAALPL | |
| SCHEMBL7934085 | 0.91 | PLA2G2A (0.39) | MAPTALDH1A1GAAHPGDACACB | |
| SCHEMBL7922057 | 0.91 | MAPT (0.42) | MAPTALDH1A1GAAHPGDRECQL | |
| SCHEMBL7958827 | 0.90 | RARB (0.42) | RARBRARAACACBTHRAKDM4E | |
| SCHEMBL7222803 | 0.88 | NPC1 (0.38) | MAPTALDH1A1HPGDACACBKDM4E | |
| SCHEMBL7249525 | 0.87 | RARB (0.39) | RARBRARAACACBRAB9ANPC1 | |
| SCHEMBL7934163 | 0.84 | KDM4E (0.45) | MAPTALDH1A1HPGDRECQLALPL | |
| SCHEMBL7246973 | 0.84 | KCNH2 (0.39) | MAPTACACBRAB9ANPC1 | |
| SCHEMBL7216131 | 0.83 | MAPT (0.36) | MAPTRARBRARAACACBALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |