Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.53 |
| ▸ | MEN1 | O00255 | 10/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957668 | 0.78 | MEN1 (0.47) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7950033 | 0.74 | ELANE (0.56) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL23146904 | 0.74 | ELANE (0.58) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7960609 | 0.72 | ESR1 (0.55) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7958244 | 0.72 | ELANE (0.57) | KMT2AMEN1MAPTRAB9APOLB | |
| SCHEMBL6026933 | 0.72 | ELANE (0.68) | KMT2AMEN1RAB9ASMN1; SMN2POLB | |
| SCHEMBL7950013 | 0.71 | ELANE (0.52) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL458844 | 0.71 | GAA (0.60) | TTRKMT2AMEN1MAPTRAB9A | |
| SCHEMBL29150900 | 0.71 | NFKB1 (0.67) | TTRKMT2AMEN1MAPTRAB9A | |
| SCHEMBL5202614 | 0.71 | MAPT (0.59) | KMT2AMEN1MAPTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6215016-B1 | HEMATOPOIETIC AGENTS; PREVENTING CYTOPENIA | TORAY INDUSTRIES, INC. (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0841063-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1998-05-13 | — | — | EP | disclosed |