Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11013826 | 0.80 | MEN1 (0.48) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL10812344 | 0.78 | MEN1 (0.47) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL7985647 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL10527436 | 0.78 | ATM (0.43) | ALDH1A1MEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL6606178 | 0.78 | PDE10A (0.46) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL7978954 | 0.77 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL7978926 | 0.77 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL9110691 | 0.75 | LMNA (0.49) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL7978886 | 0.74 | KMT2A (0.48) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL10811812 | 0.74 | CYP2D6 (0.48) | ALDH1A1MEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| CN-1252068-A | 3-piperidyl-4-oxoquinazoline derivatives and pharmaceutical compositions containing the same | JAPAN TOBACCO INC (JP) | 2000-05-03 | — | — | CN | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |