Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | APAF1 | O14727 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978926 | 0.83 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1TSHRNPSR1 | |
| SCHEMBL7985647 | 0.75 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1TSHRNPSR1 | |
| SCHEMBL7978954 | 0.74 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1TSHRNPSR1 | |
| SCHEMBL741752 | 0.72 | NPSR1 (0.64) | ALDH1A1KMT2AMEN1TSHRNPSR1 | |
| SCHEMBL7978886 | 0.72 | KMT2A (0.48) | ALDH1A1KMT2AMEN1TSHRNPSR1 | |
| SCHEMBL24654512 | 0.71 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1TSHRNPSR1 | |
| SCHEMBL8691853 | 0.71 | KMT2A (0.41) | ALDH1A1KMT2AMEN1TSHRNPSR1 | |
| SCHEMBL7978951 | 0.71 | POLQ (0.42) | ALDH1A1KMT2AMEN1TSHRNPSR1 | |
| SCHEMBL9518578 | 0.70 | NPSR1 (0.47) | ALDH1A1KMT2AMEN1TSHRNPSR1 | |
| SCHEMBL28215851 | 0.70 | KMT2A (0.53) | ALDH1A1KMT2AMEN1TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |