Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | ADAMTS7 | Q9UKP4 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 3/20 | 0.32 |
| ▸ | CCR1 | P32246 | 6/20 | 0.32 |
| ▸ | CCR2 | P41597 | 6/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934430 | 0.90 | AKR1C2 (0.36) | PTGER3MCL1ADAMTS7BRD4CCR1 | |
| SCHEMBL6026240 | 0.80 | MCL1 (0.35) | MCL1ADAMTS7BRD4CCNCCDK8 | |
| SCHEMBL7971858 | 0.75 | MCL1 (0.38) | PTGER3MCL1CCNCCDK8KMT2A | |
| SCHEMBL7968985 | 0.71 | NOTUM (0.39) | S1PR1KMT2ANPC1RAB9AGAA | |
| SCHEMBL7956300 | 0.71 | LMNA (0.43) | MCL1CCNCCDK8KMT2AMEN1 | |
| SCHEMBL6931613 | 0.66 | AKR1C2 (0.42) | PTGER3MCL1KMT2AMEN1 | |
| SCHEMBL7591686 | 0.66 | AKR1C2 (0.42) | PTGER3MCL1KMT2AMEN1 | |
| SCHEMBL6026778 | 0.63 | BACE1 (0.36) | NPC1RAB9A | |
| SCHEMBL7586371 | 0.63 | AKR1C2 (0.41) | MCL1CCNCCDK8KMT2AMEN1 | |
| SCHEMBL6934449 | 0.63 | AKR1C2 (0.41) | MCL1CCNCCDK8KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |