Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6931613 | 0.86 | AKR1C2 (0.42) | MCL1PTGER3POLBMEN1KMT2A | |
| SCHEMBL7591686 | 0.86 | AKR1C2 (0.42) | MCL1PTGER3POLBMEN1KMT2A | |
| SCHEMBL7956300 | 0.79 | LMNA (0.43) | MCL1POLBLMNAMAPTALOX12 | |
| SCHEMBL6026481 | 0.79 | MCL1 (0.41) | MCL1PTGER3POLBLMNAMAPT | |
| SCHEMBL6931685 | 0.77 | PGR (0.43) | PTGER3PGRARHCAR2 | |
| SCHEMBL7956291 | 0.76 | PTGER3 (0.40) | MCL1PTGER3LMNAMAPTMAOA | |
| SCHEMBL7968980 | 0.75 | PTGER3 (0.35) | MCL1PTGER3MEN1KMT2AMAOA | |
| SCHEMBL6026165 | 0.73 | HSD17B1 (0.38) | POLBLMNAMAPTMEN1KMT2A | |
| SCHEMBL6932927 | 0.70 | CHRNA1 (0.42) | MCL1MAPTMEN1KMT2AHCAR2 | |
| SCHEMBL7983353 | 0.70 | CHRNA1 (0.42) | MCL1MAPTMEN1KMT2AHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |