Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CRHBP | P24387 | 2/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969661 | 0.90 | PTGDR2 (0.41) | CA12CA9CA2KIF11LMNA | |
| SCHEMBL7934057 | 0.87 | SLC6A3 (0.40) | CA12CA9KDM4EALDH1A1HPGD | |
| SCHEMBL7975083 | 0.87 | CA12 (0.39) | CA12CA9CA2NPSR1KDM4E | |
| SCHEMBL7931169 | 0.87 | CA12 (0.39) | CA12CA9KIF11PTGDR2MMP1 | |
| SCHEMBL7934163 | 0.86 | KDM4E (0.45) | CA12CA9CA2KDM4EALDH1A1 | |
| SCHEMBL7969353 | 0.86 | SLC6A3 (0.40) | CA12CA9CA2SLC6A2NPSR1 | |
| SCHEMBL7922070 | 0.85 | L3MBTL1 (0.35) | CA12CA9CA2EGFRKDM4E | |
| SCHEMBL7934116 | 0.85 | CTSL (0.39) | CA12CA9ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7969027 | 0.84 | CTSL (0.41) | CA12CA9BRD4KIF11 | |
| SCHEMBL7934122 | 0.84 | HSP90AA1 (0.34) | CA12CA9CA2SLC6A2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |