Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7931561 | 0.89 | SLC6A3 (0.45) | SLC6A3SLC6A2SLC6A4MAPTLMNA | |
| SCHEMBL7934057 | 0.89 | SLC6A3 (0.40) | SLC6A3CA12CA9SLC6A4MAPT | |
| SCHEMBL7975083 | 0.89 | CA12 (0.39) | CA12CA9CA2POLBMAPT | |
| SCHEMBL7934122 | 0.88 | HSP90AA1 (0.34) | SLC6A3CA12CA9CA2SLC6A2 | |
| SCHEMBL7934163 | 0.88 | KDM4E (0.45) | SLC6A3CA12CA9CA2MAPT | |
| SCHEMBL7922070 | 0.87 | L3MBTL1 (0.35) | CA12CA9CA2MAPTKDM4E | |
| SCHEMBL7934116 | 0.87 | CTSL (0.39) | CA12CA9POLBMAPTALDH1A1 | |
| SCHEMBL7969052 | 0.86 | CA12 (0.42) | CA12CA9CA2SLC6A2LMNA | |
| SCHEMBL7969661 | 0.85 | PTGDR2 (0.41) | CA12CA9CA2LMNA | |
| SCHEMBL3499284 | 0.85 | ALAD (0.35) | CA12POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |