Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969086 | 0.87 | RAB9A (0.38) | RAB9AGAANPC1CLK1OPRD1 | |
| SCHEMBL7957883 | 0.86 | RAB9A (0.43) | RAB9AGAANPC1CLK1OPRD1 | |
| SCHEMBL7973745 | 0.77 | OPRD1 (0.45) | OPRD1 | |
| SCHEMBL7970812 | 0.74 | CYP1A2 (0.48) | RAB9AGAAOPRD1CYP1A2CYP3A4 | |
| SCHEMBL7967851 | 0.72 | CYP1A2 (0.45) | OPRD1CYP1A2CYP3A4 | |
| SCHEMBL7968921 | 0.72 | OPRD1 (0.60) | OPRD1CYP1A2CYP3A4 | |
| SCHEMBL7967499 | 0.71 | RAB9A (0.40) | RAB9AGAANPC1CLK1OPRD1 | |
| SCHEMBL7957969 | 0.69 | RAB9A (0.48) | RAB9AGAANPC1CLK1 | |
| SCHEMBL7958101 | 0.69 | RAB9A (0.47) | RAB9AGAANPC1CLK1 | |
| SCHEMBL7958158 | 0.68 | OPRD1 (0.57) | OPRD1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200978-B1 | FOR PREVENTING OR TREATING INFLAMMATORY DISEASES SUCH AS ARTHRITIS, PSORIASIS, ASTHMA, OR INFLAMMATORY BOWEL DISEASE, DISORDERS OF RESPIRATORY FUNCTION, GASTROINTESTINAL DISORDERS SUCH AS FUNCTIONAL BOWEL DISEASE, AS ANALGESICS | PFIZER INC. | 2001-03-13 | — | — | US | disclosed |