Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 7/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | COMT | P21964 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930001 | 0.82 | ALDH1A1 (0.45) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6931344 | 0.82 | ALDH1A1 (0.45) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6929228 | 0.80 | ALDH1A1 (0.47) | ARALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL6933633 | 0.80 | ALDH1A1 (0.43) | ALDH1A1LMNACYP2C9CYP2C19TNKS | |
| SCHEMBL6026843 | 0.76 | ME2 (0.46) | ALDH1A1LMNAMAOA | |
| SCHEMBL7956394 | 0.76 | EGFR (0.46) | ALDH1A1LMNA | |
| SCHEMBL6933173 | 0.75 | AHR (0.41) | ALDH1A1LMNACYP1B1MAOB | |
| SCHEMBL7966819 | 0.75 | HSP90AA1 (0.42) | ALDH1A1LMNA | |
| SCHEMBL7591786 | 0.75 | AHR (0.41) | ALDH1A1LMNACYP1B1MAOB | |
| SCHEMBL6025954 | 0.75 | ALDH1A1 (0.46) | ALDH1A1LMNAPARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |