Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 5/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22576217 | 0.84 | ALDH1A1 (0.55) | ALDH1A1CYP3A4MBOAT4HSP90AB1 | |
| SCHEMBL7969373 | 0.80 | CYP1A2 (0.44) | CYP11B1CYP11B2 | |
| SCHEMBL19880302 | 0.77 | GRM5 (0.43) | PDE4BPDE4DLOXL2CYP17A1CYP11B1 | |
| SCHEMBL28043533 | 0.77 | CYP17A1 (0.47) | PDE4BPDE4DLOXL2CYP17A1CYP11B1 | |
| SCHEMBL7971464 | 0.74 | GAA (0.45) | ALDH1A1MAPT | |
| SCHEMBL28438099 | 0.74 | SLC6A4 (0.46) | ALDH1A1CYP3A4MBOAT4MAPTHSP90AB1 | |
| SCHEMBL24254614 | 0.72 | KDM4E (0.55) | CYP11B1CYP11B2ALDH1A1MAPT | |
| SCHEMBL5209337 | 0.70 | RAB9A (0.49) | ALDH1A1CYP3A4MAPT | |
| SCHEMBL378811 | 0.70 | — | — | |
| SCHEMBL29712341 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |